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Sensory hair cell loss

Sensory hair cell loss is the major cause of hearing loss and balance disorders. The postnatal mammalian inner ear harbors progenitor cells which have the potential for hair cell regeneration and hearing recovery. Scientists from the Eaton-Peabody Laboratories at Massachusetts Eye and Ear/Harvard Medical School and Fudan University, Shanghai, China, have shown that blocking the Notch pathway, known to control the elaborate hair cell distribution in the inner ear, plays an essential role that determines cochlear progenitor cell proliferation capacity. According to Massachusetts Eye and Ear Infirmary. "Blocking Notch pathway leads to a new route to hair cell regeneration to restore hearing." ScienceDaily.   ScienceDaily, 22 December 2014.  
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